Enfin, un comprimé anti-poux ?
Ivermectine : retenez bien ce nom ! Cette molécule, utilisée pour le traitement contre la gale, va peut-être mettre fin à la terrible contagion dont sont victimes chaque année des milliers enfants : les poux !
Ces parasites, qui nous contaminent depuis la nuit des temps, ont développé des stratégies pour survivre en milieux hostiles en faisant évoluer leur patrimoine génétique. Au final, ils sont de plus en plus résistants aux produits insecticides contenus dans les lotions… Et il est très difficile de s’en débarrasser. Fort de ce constat, le professeur Olivier Chosidow (hôpital Tenon, Paris), en collaboration avec Bruno Giraudeau chercheur à l’Inserm, ont mené des recherches (1) en comparant l’efficacité d’une lotion classique (à base de malathion) à celle d’un comprimé d’ivermectine. Pour cela, ils ont testé les 2 produits, 2 fois à 7 jours d’intervalle, sur 812 personnes contaminées provenant de 376 familles. Résultat : 95 % des personnes ayant suivi le traitement par ivermectine étaient débarrassés des poux en 15 jours, contre seulement 85 % pour les individus traités par malathion. "Lorsque les traitements classiques contre les poux ne fonctionnent pas, la prise d'ivermectine deux fois à 7 jours d'intervalle offre de très bons résultats et représente une réelle alternative aux lotions anti-poux classiques", indique le Pr Chosidow. Bien que très connue et bien tolérée, la molécule, assez puissante, sera destinée aux enfants sur lesquels tous les autres traitements ont échoué.
(1) Les travaux de recherche ont été publiés dans l’édition du 11 mars du New England of Medicine.
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From the very circumstance of its being larger, sir. We shall have no occasion to open the windows at all-not once the whole evening; and it is that dreadful habit of opening the windows, letting in cold air upon heated bodies, which (as you well know, sir) does the mischief. Jealousy of Mr Elliot! It was the only intelligible motive. I am glad of it. John has charming spirits, has not he? I dare say Mr. Crawford would take my two nieces and me in his barouche, and Edmund can go on horseback, you know, sister, and Fanny will stay at home with you." We misunderstood each other: he believed me more to blame than I really was; I considered his interference less excusable than I now find it. I have a real regard for him, and was beyond expression mortified to find it, as I thought, so ill bestowed We were both warm, and of course both to blame. His resolution of leaving Churchhill is consistent with his general eagerness. When I understood his intention, however, and at the same time began to think that we had been perhaps equally mistaken in each other's meaning, I resolved to have an explanation before it was too late. For any member of your family I must always feel a degree of affection, and I own it would have sensibly hurt me if my acquaintance with Mr. De Courcy had ended so gloomily. I have now only to say further, that as I am convinced of Frederica's having a reasonable dislike to Sir James, I shall instantly inform him that he must give up all hope of her. I reproach myself for having even, though innocently, made her unhappy on that score. She shall have all the retribution in my power to make; if she value her own happiness as much as I do, if she judge wisely, and command herself as she ought, she may now be easy. Excuse me, my dearest sister, for thus trespassing on your time, but I owe it to my own character; and after this explanation I trust I am in no danger of sinking in your opinion. I could have said, ""Not much, indeed!"" but I left her almost in silence. It was the greatest stretch of forbearance I could practise. I could not have stopped myself had I begun. Her assurance! her deceit! but I will not allow myself to dwell on them; they will strike you sufficiently. My heart sickens within me. As soon as I was tolerably composed I returned to the parlour. Sir James's carriage was at the door, and he, merry as usual, soon afterwards took his leave. How easily does her ladyship encourage or dismiss a lover! In spite of this release, Frederica still looks unhappy: still fearful, perhaps, of her mother's anger; and though dreading my brother's departure, jealous, it may be, of his staying. I see how closely she observes him and Lady Susan, poor girl! I have now no hope for her."
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I do not know what it is all about. I am never to see my cards; and Mr. Crawford does all the rest." He thanked her with all his heart, and continued some time to speak with serious feeling of his gratitude and happiness. Alas! why do you thus so cruelly connive at the projected Misery of her and of yourself by delaying to communicate that scheme which had doubtless long possessed your imagination? A secret Union will at once secure the felicity of both. It is particularly incumbent on those who never change their opinion, to be secure of judging properly at first. It was soon pain upon pain, confusion upon confusion; for they were hardly in the High Street before they met her father, whose appearance was not the better from its being Saturday. He stopt; and, ungentlemanlike as he looked, Fanny was obliged to introduce him to Mr. Crawford. I am certain she likes the Fellow. My Father desires us not to be in a hurry, as perhaps if we wait a few months both he and Lady Lesley will do themselves the pleasure of attending us.
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They were sneering and negligent. Emma hoped it must rapidly work Harriet's cure; but the sensations which could prompt such behaviour sunk them both very much.-It was not to be doubted that poor Harriet's attachment had been an offering to conjugal unreserve, and her own share in the story, under a colouring the least favourable to her and the most soothing to him, had in all likelihood been given also. She was, of course, the object of their joint dislike.-When they had nothing else to say, it must be always easy to begin abusing Miss Woodhouse; and the enmity which they dared not shew in open disrespect to her, found a broader vent in contemptuous treatment of Harriet. But, my dear Marianne, as it has already exposed you to some very impertinent remarks, do you not now begin to doubt the discretion of your own conduct? Chapter 29 What can Sir Thomas and Edmund together do, what do they do for her happiness, comfort, honour, and dignity in the world, to what I shall do?" I collect, said Miss Crawford, "that Sotherton is an old place, and a place of some grandeur. In vain I have struggled. It will not do. My feelings will not be repressed. You must allow me to tell you how ardently I admire and love you. Oh! Don't defend her! And then the brother, he, who had appeared so attached to you! Good heavens! Well, some people's feelings are incomprehensible. And so he hardly looked once at you the whole day?
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She felt how unprofitable contention would be. He was anxious, while vindicating himself, to say nothing unkind of the others: but there was only one amongst them whose conduct he could mention without some necessity of defence or palliation. "We have all been more or less to blame," said he, "every one of us, excepting Fanny. For two days Mrs. Morland allowed it to pass even without a hint; but when a third night's rest had neither restored her cheerfulness, improved her in useful activity, nor given her a greater inclination for needlework, she could no longer refrain from the gentle reproof of, "My dear Catherine, I am afraid you are growing quite a fine lady. I do not know when poor Richard's cravats would be done, if he had no friend but you. Your head runs too much upon Bath; but there is a time for everything-a time for balls and plays, and a time for work. You have had a long run of amusement, and now you must try to be useful." Oh! cried Miss Bingley, "Charles writes in the most careless way imaginable. He leaves out half his words, and blots the rest." You make me laugh, Charlotte; but it is not sound. You know it is not sound, and that you would never act in this way yourself.
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Can you seriously ask me, Harriet, whether I imagined him attached to another woman at the very time that I was-tacitly, if not openly-encouraging you to give way to your own feelings?-I never had the slightest suspicion, till within the last hour, of Mr. Frank Churchill's having the least regard for Jane Fairfax. You may be very sure that if I had, I should have cautioned you accordingly." This speech at first puzzled Mrs. Jennings exceedingly. Why Mr. Ferrars was to have been written to about it in such a hurry, she could not immediately comprehend. A few moments' reflection, however, produced a very happy idea, and she exclaimed;— I am,-she answered-"I am fatigued; but it is not the sort of fatigue-quick walking will refresh me.-Miss Woodhouse, we all know at times what it is to be wearied in spirits. Mine, I confess, are exhausted. The greatest kindness you can shew me, will be to let me have my own way, and only say that I am gone when it is necessary." As you do us such ample justice now, said Emma, laughing, "I will venture to ask, whether you did not come a little doubtfully at first? The youthful infatuation of nineteen would naturally blind him to every thing but her beauty and good nature; but the four succeeding years—years, which if rationally spent, give such improvement to the understanding, must have opened his eyes to her defects of education, while the same period of time, spent on her side in inferior society and more frivolous pursuits, had perhaps robbed her of that simplicity which might once have given an interesting character to her beauty. Edmund was close to her; he was speaking to her; he was evidently directing her management of the bridle; he had hold of her hand; she saw it, or the imagination supplied what the eye could not reach. She must not wonder at all this; what could be more natural than that Edmund should be making himself useful, and proving his good-nature by any one? She could not but think, indeed, that Mr. Crawford might as well have saved him the trouble; that it would have been particularly proper and becoming in a brother to have done it himself; but Mr. Crawford, with all his boasted good-nature, and all his coachmanship, probably knew nothing of the matter, and had no active kindness in comparison of Edmund. She began to think it rather hard upon the mare to have such double duty; if she were forgotten, the poor mare should be remembered.
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What do you mean, Hill? We have heard nothing from town. He knew her to be very timid, and exceedingly nervous; and thought it not improbable that her mind might be in such a state as a little time, a little pressing, a little patience, and a little impatience, a judicious mixture of all on the lover's side, might work their usual effect on. If the gentleman would but persevere, if he had but love enough to persevere, Sir Thomas began to have hopes; and these reflections having passed across his mind and cheered it, "Well," said he, in a tone of becoming gravity, but of less anger, "well, child, dry up your tears. There is no use in these tears; they can do no good. You must now come downstairs with me. And of this place, thought she, "I might have been mistress! With these rooms I might now have been familiarly acquainted! Instead of viewing them as a stranger, I might have rejoiced in them as my own, and welcomed to them as visitors my uncle and aunt. But no,"-recollecting herself-"that could never be; my uncle and aunt would have been lost to me; I should not have been allowed to invite them." I have no doubt of it, replied Marianne. I dare say he will be in parliament soon. When Sir Thomas comes, I dare say he will be in for some borough, but there has been nobody to put him in the way of doing anything yet. What, none of you? My love, said her mother, "you must not be offended with Elinor—she was only in jest. I should scold her myself, if she were capable of wishing to check the delight of your conversation with our new friend."— Marianne was softened in a moment.
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The wish was rather eager than lasting. He was roused from the reverie of retrospection and regret produced by it, by some inquiry from Edmund as to his plans for the next day's hunting; and he found it was as well to be a man of fortune at once with horses and grooms at his command. I am not now to learn, replied Mr. Collins, with a formal wave of the hand, "that it is usual with young ladies to reject the addresses of the man whom they secretly mean to accept, when he first applies for their favour; and that sometimes the refusal is repeated a second, or even a third time. I am therefore by no means discouraged by what you have just said, and shall hope to lead you to the altar ere long." Elinor told him the number of the house. "What can it be, Miss Woodhouse?-what can it be? I have not an idea-I cannot guess it in the least. What can it possibly be? Do try to find it out, Miss Woodhouse. Do help me. I never saw any thing so hard. Is it kingdom? I wonder who the friend was-and who could be the young lady. Do you think it is a good one? Can it be woman? With something of consciousness he shook his head at his sister, and laughingly replied, "I cannot say there was much done at Sotherton; but it was a hot day, and we were all walking after each other, and bewildered."
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Elizabeth, feeling all the more than common awkwardness and anxiety of his situation, now forced herself to speak; and immediately, though not very fluently, gave him to understand that her sentiments had undergone so material a change, since the period to which he alluded, as to make her receive with gratitude and pleasure his present assurances. The happiness which this reply produced, was such as he had probably never felt before; and he expressed himself on the occasion as sensibly and as warmly as a man violently in love can be supposed to do. Had Elizabeth been able to encounter his eye, she might have seen how well the expression of heartfelt delight, diffused over his face, became him; but, though she could not look, she could listen, and he told her of feelings, which, in proving of what importance she was to him, made his affection every moment more valuable. Her companion looked at her keenly; and gathering greater spirit from the blush soon produced from such a look, only said, "He is best off as he is," and turned the subject. I shall have no difficulty, I suppose, in finding the house; though Fairfax, I believe, is not the proper name-I should rather say Barnes, or Bates. Do you know any family of that name?" Chapter 3 He coloured as he replied, "You are very kind, but I have no idea of returning into Devonshire immediately. My visits to Mrs. Smith are never repeated within the twelvemonth." Then you would be very ill-bred, cried Mr. Palmer.
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That happened before I went to sea in the year six, occurred in the course of the first evening they spent together: and though his voice did not falter, and though she had no reason to suppose his eye wandering towards her while he spoke, Anne felt the utter impossibility, from her knowledge of his mind, that he could be unvisited by remembrance any more than herself. But if we only wait a few minutes, there will be no danger of our seeing them at all. "Oh! depend upon it, your aunt can do very well without you, or you would not be allowed to go. I shall be here, so you may be quite easy about your aunt. And I hope you will have a very agreeable day, and find it all mighty delightful . One is nothing, indeed. You remember the Gregorys; they are grown up amazing fine girls, but they will hardly speak to me, because Lucy is courted by a lieutenant." But as we drove too rapidly to allow them to answer my repeated Enquiries, I gained little, or indeed, no information concerning him. "Where am I to drive?" said the Postilion. "To Newgate Gentle Youth (replied I), to see Augustus." "Oh! no, no, (exclaimed Sophia) I cannot go to Newgate; I shall not be able to support the sight of my Augustus in so cruel a confinement-my feelings are sufficiently shocked by the RECITAL, of his Distress, but to behold it will overpower my Sensibility." As I perfectly agreed with her in the Justice of her Sentiments the Postilion was instantly directed to return into the Country. You may perhaps have been somewhat surprised my Dearest Marianne, that in the Distress I then endured, destitute of any support, and unprovided with any Habitation, I should never once have remembered my Father and Mother or my paternal Cottage in the Vale of Uske. To account for this seeming forgetfullness I must inform you of a trifling circumstance concerning them which I have as yet never mentioned. The death of my Parents a few weeks after my Departure, is the circumstance I allude to. By their decease I became the lawfull Inheritress of their House and Fortune. But alas! the House had never been their own and their Fortune had only been an Annuity on their own Lives. Such is the Depravity of the World! To your Mother I should have returned with Pleasure, should have been happy to have introduced to her, my charming Sophia and should with Chearfullness have passed the remainder of my Life in their dear Society in the Vale of Uske, had not one obstacle to the execution of so agreable a scheme, intervened; which was the Marriage and Removal of your Mother to a distant part of Ireland. Her eye was eagerly taking in everything within her reach; and after being at some pains to get a view of the house, and observing that "it was a sort of building which she could not look at but with respect," she added, "Now, where is the avenue? The house fronts the east, I perceive. He set off accordingly.
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